Kiyotaka Kugiyama Selected Research

sematilide

8/2002

Comparison of the in vivo electrophysiological and proarrhythmic effects of amiodarone with those of a selective class III drug, sematilide, using a canine chronic atrioventricular block model.

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Kiyotaka Kugiyama Research Topics

Disease

24	Coronary Artery Disease (Coronary Atherosclerosis) 09/2022 - 06/2004
23	Myocardial Infarction 04/2021 - 06/2002
10	Cardiovascular Diseases (Cardiovascular Disease) 09/2022 - 07/2002
8	Heart Failure 09/2022 - 10/2004
6	Infarction (Infarctions) 04/2021 - 10/2004
6	Myocardial Ischemia (Ischemic Heart Diseases) 11/2013 - 09/2002
6	Reperfusion Injury 05/2012 - 07/2002
5	Atherosclerosis 01/2020 - 01/2003
5	Left Ventricular Dysfunction 05/2016 - 05/2002
4	Atherosclerotic Plaque (Atheroma) 12/2019 - 07/2004
4	Acute Coronary Syndrome 01/2014 - 04/2008
4	Type 2 Diabetes Mellitus (MODY) 01/2012 - 05/2005
3	Hypertension (High Blood Pressure) 01/2022 - 04/2011
3	ST Elevation Myocardial Infarction 04/2021 - 12/2019
3	Diabetes Mellitus 04/2011 - 06/2004
2	Myocarditis (Carditis) 06/2020 - 08/2013
2	Aneurysm (Aneurysms) 01/2020 - 08/2017
2	Hyperlipidemias (Hyperlipidemia) 01/2020 - 08/2007
2	Thrombosis (Thrombus) 09/2019 - 10/2013
2	Insulin Resistance 12/2013 - 12/2007
2	Carotid Stenosis (Carotid Artery Stenosis) 01/2012 - 04/2009
2	Glucose Intolerance 12/2010 - 10/2007
2	Pulmonary Edema 10/2010 - 05/2010
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2009 - 08/2005
2	Spasm (Spasms) 05/2008 - 07/2002
2	Ischemia 10/2007 - 04/2004
2	Microvascular Angina (Cardiac Syndrome X) 07/2007 - 12/2006
2	Neoplasms (Cancer) 10/2005 - 09/2005
1	Adenocarcinoma of Lung 09/2021
1	Lymphoma (Lymphomas) 09/2021
1	Carcinoma (Carcinomatosis) 09/2021
1	Obesity 01/2020
1	Aortic Dissection 01/2020
1	Respiratory Insufficiency (Respiratory Failure) 01/2018
1	Dyspnea (Shortness of Breath) 01/2018
1	Coronary Vasospasm (Coronary Artery Vasospasm) 01/2018
1	Cataract (Cataracts) 01/2018
1	Lung Injury 01/2018
1	Fever (Fevers) 01/2018

Drug/Important Bio-Agent (IBA)

11	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 09/2022 - 08/2007
10	Lipoproteins (Lipoprotein)IBA 01/2020 - 06/2004
8	Secretory Phospholipases A2IBA 01/2020 - 06/2008
8	CholesterolIBA 01/2020 - 06/2004
7	Acetylcholine (Acetylcholine Chloride)FDA Link 04/2021 - 07/2002
6	LipidsIBA 01/2021 - 01/2006
6	AdiponectinIBA 02/2009 - 06/2006
5	EnzymesIBA 08/2020 - 09/2003
5	Pharmaceutical PreparationsIBA 09/2019 - 08/2002
5	Glutamate-Cysteine LigaseIBA 02/2013 - 06/2002
4	Proteins (Proteins, Gene)FDA Link 11/2021 - 06/2006
4	oxidized low density lipoproteinIBA 01/2020 - 09/2011
4	MetalsIBA 09/2019 - 08/2005
3	C-Reactive ProteinIBA 01/2022 - 05/2007
3	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2021 - 07/2002
3	Phospholipase A2 ReceptorsIBA 06/2020 - 08/2013
3	Sirolimus (Rapamycin)FDA Link 01/2020 - 10/2007
3	EicosanoidsIBA 10/2013 - 10/2010
3	Brain Natriuretic Peptide (Natrecor)FDA Link 07/2012 - 05/2002
3	Leukotriene B4IBA 05/2012 - 05/2010
3	Phospholipases (Phospholipase)IBA 05/2012 - 06/2008
3	ThromboxanesIBA 05/2012 - 05/2010
3	2,5-dichloro-4-bromophenol (B 2)IBA 05/2012 - 05/2010
3	Triglycerides (Triacylglycerol)IBA 01/2009 - 08/2005
3	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2007 - 07/2006
2	Glutathione (Reduced Glutathione)IBA 11/2021 - 09/2003
2	ChemokinesIBA 07/2019 - 01/2018
2	LDL CholesterolIBA 01/2019 - 09/2011
2	Group X Phospholipases A2IBA 01/2012 - 06/2008
2	Pravastatin (Pravachol)FDA LinkGeneric 08/2010 - 10/2007
2	HDL LipoproteinsIBA 04/2009 - 05/2007
2	Adenosine Triphosphate (ATP)IBA 01/2009 - 08/2005
2	Peroxidase (Myeloperoxidase)IBA 06/2008 - 07/2004
2	Natriuretic PeptidesIBA 10/2004 - 05/2002
1	Cysteine (L-Cysteine)FDA Link 11/2021
1	Phosphotransferases (Kinase)IBA 09/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 09/2021
1	omega-Chloroacetophenone (Mace)IBA 04/2021
1	ImmunosorbentsIBA 08/2020
1	FollistatinIBA 08/2020
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 06/2020
1	Dinoprostone (PGE2)FDA Link 06/2020
1	Angiotensin IIIBA 01/2020
1	Creatine Kinase (Creatine Phosphokinase)IBA 01/2020
1	Phospholipids (Phosphatides)FDA LinkGeneric 01/2020
1	Protein SIBA 01/2020
1	antineoplaston A10 (A 10)IBA 01/2020
1	Linoleic Acid (Linoleate)IBA 01/2020
1	PolymersIBA 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2018
1	Dosage Forms (Dosage Form)IBA 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2018
1	Ophthalmic Solutions (Eye Drops)IBA 01/2018
1	Angiotensin Receptor AntagonistsIBA 01/2018

Therapy/Procedure

19	Therapeutics 09/2022 - 07/2002
9	Stents 01/2022 - 08/2005
7	Percutaneous Coronary Intervention 09/2022 - 03/2008
3	Renal Dialysis (Hemodialysis) 01/2022 - 10/2012
2	Catheters 10/2013 - 05/2002
2	Ligation 10/2010 - 12/2007
1	Secondary Prevention 01/2021